The Manchester Centre for Integrative Systems Biology (MCISB) is in the process of measuring the kinetic and binding constants associated with enzyme reactions in metabolic pathways in the yeast, Saccharomyces cerevisiae. Quantitative models of these metabolic pathways are being integrated with transcriptomic, proteomic and metabolomic data by workflows that have been constructed and enacted using Taverna.
Publications
A poster by Peter Li describing the systems biology workflows was presented at the International Conference of Systems Biology 2006 and he has written several publications about the work.
Many of the workflows make use of Systems Biology Markup Language (SBML) as described in the paper Automated manipulation of systems biology models using libSBML within Taverna workflows by Li et al.
An example workflow using SBML is available on myExperiment.
